Who we are?
Pharmaseed is a GLP-certified pre-clinical and early clinical CRO specializing in translational and regenerative studies.
Pharmaseed is equipped for the execution of NCE studies, biologics and medical-devices as well as conducting and following through from the development stage until first-in-man trials. These studies include safety and efficacy evaluation in various animal models in addition to complementary in-vitro/ex-vivo models and on-site human anatomy services.
Pharmaseed’s expertise in preclinical studies lies mostly in the following areas:
Cardio/vascular, Immuno-Oncology, Stem cell and Cellular Therapeutics, Microbiome research, Infectious Diseases, and CNS.
Why work with us?
- Innovative technology requires an innovative CRO
- Pharmaseed is Israel’s largest GLP - certified pre-clinical and early clinical CRO, specializing in translational projects of all stages, mastering the “end in mind” approach.
- With over 20 years of experience, a professional team which includes over 13 PHD and postdoctoral level researchers who have held key positions within the life sciences industry, state of the art laboratory, in house vivarium, BL2 safety unit and a modern in vitro laboratory, we are conducting multidisciplinary, complex studies covering molecular, cellular and in vivo needs according to the highest ethical and regulatory standards.
- During our 20 years of activity, we have learned how to adjust and balance creativity and flexibility, maintaining rigid ethics and quality demands.
- Pharmaseed provides in depth knowledge and experience in planning and interpreting study results. We offer high end “one stop shop” R&D services, hence, multiplying the chances of transforming your product from a mere idea, to a real sustainable technology.
Safety & ADME
Whether your compound is an original small molecule or bioequivalent generic, injectable large molecule or biosimilar – our experts are true specialists.
Our services support an array of therapeutic disciplines
Cannabis based therapy
Microbiome
Pharmaceuticals
Medical devices
Biological therapy
Nutraceuticals
Cell & Gene based Therapy
Our services utilize various animal species
Yeast
C-elegance
Drosophila
Zebrafish
Rat-mice
Rabbit
Pig
Human
Yeast
C-elegans
Drosophila
Zebrafish
Rat-mice
Rabbit
Pig
Human
REGULATORY SERVICES
- Regulatory, Writing & Strategy
- Nonclinical and Clinical Development Plans
- Advice and Design of IND-enabling Studies
- Toxicology, Pharmacology, In-Vivo, In-Vitro, DDI
- IND Authoring (full or sections), Review, Publishing & Submission (CTD / eCTD)
- Regulatory Agency RFIs, Meetings, Planning & Representation
- Guidance Document Interpretation
ADME SERVICES
- Noncompartmental Analysis (GLP and Non-GLP)
- Candidate Selection
- PK/PD/TK/ADME
- Biodistribution
- Model-based Allometric Scaling to Predict Human Exposure
- Understanding Concentration / Response for Dose Selection
- Study Design Simulations
- Physiologically-based Pharmacokinetic Modeling (PBPK)
Per Year
Personnel