Infectious Disease & Microbiome Models
Pathogen:
As a CRO, Pharmaseed is committed to assisting in the fight against various pathogens that cause high prevalence diseases, including MRSA, Influenza, Pneumonia, Covid-19, and others. Extensive experience gives our team an in-depth understanding of the complexities of infectious diseases, expertise in feasibility assessment and site selection, protocol design, and establishment of an appropriate animal model in addition to our already established models.
Microbiome:
Pharmaseed’s Bio-Safety Level 2 (BSL2) facilities enable us to conduct more than just infectious diseases studies. The microbiome is a fast-growing field that is increasingly being associated with human health conditions. Manipulation of the human microbiome has shown therapeutic potential in cancer, inflammation, metabolic and neurological diseases.
Our services support an array of therapeutic disciplines
Cell & Gene based Therapy
Biological therapy
Cannabis based therapy
Microbiome
Pharmaceuticals
Medical devices
Nutraceuticals
Our Infectious Disease & Microbiome Models
Pathogen:
- Infectious agent available: E.coli, Klebsiella, MRSA, Pseudomonas.
- Species available: Mouse.
- Standard assessments: Body weight, clinical signs, microbial burden determination (CFU), histology.
- Additional assessments: Kidney function evaluation.
- Model available: Cecal Ligation and Puncture (CLP).
- Infectious agants available: E.coli, Klebsiella, MRSA, Pseudomonas.
- Species available: Mouse, Rat.
- Standard assessments: Body weight, clinical signs, survival.
- Additional assessments: microbial burden determination (CFU).
- Infectious agent available: Klebsiella, Pseudomonas.
- Species available: Mouse.
- Standard assessments: Body weight, clinical signs, survival, microbial burden determination (CFU), Histology.
- Additional assessments: Upon request.
- Models available: Bacteria induced IBD.
- Species available: Mouse, Rat.
- Standard assessments: Body weight, clinical signs, scoring, microbial burden determination (CFU), histology.
- Additional assessments: Cytokine levels (ELISA), PCR.
- Infectious agents available: E.coli, Klebsiella, Pseudomonas, Staphylococcus (including MRSA).
- Species available: Mouse, Rat, Pig.
- Standard assessments: Body weight, clinical signs, wound closure measurement.
- Additional assessments: Histology.
Microbiome:
- Cancers available: Breast, Colon, Melanoma.
- Species available: Mouse.
- Standard assessments: Body weight, clinical signs, tumor measurement, microbial burden determination (CFU), PCR.
- Additional assessments: Histology, tumor markers (ELISA, immunostaining).
- Infectious agent available: Influenza, Covid19.
- Species available: Mouse.
- Standard assessments: Body weight, clinical signs, survival.
- Additional assessments: Blood chemistry and biochemistry, cytokine levels (ELISA).
Additional clinical indications related to microbiome see:
Research outcomes - examples
